Functional Innovation KO Atlas Reuse Test

Why It Matters

The Functional Innovation KO Atlas is exactly the kind of derived product that should compound across projects if it is useful. It needs a first reuse test that asks whether it changes interpretation, not just whether it can be joined.

Review Brief

What changed: the paired product page now asks whether stable artifacts and downstream consumers exist.

Why review matters: this opportunity should decide whether the KO atlas is a reusable layer or a project-specific synthesis.

Evidence to inspect:

• Functional Innovation KO Atlas for artifacts and caveats.
• Pangenome Openness Metrics for a likely join partner.
• pangenome_pathway_ecology, pangenome_pathway_geography, and pathway_capability_dependency for consumer contexts.

Questions for reviewers:

• What downstream analysis would fail or improve because this product exists?
• Which resolution should the first reuse test use?
• Does KO innovation add signal beyond baseline pathway counts?
• What artifact needs to exist before this product can be promoted?

Evidence Base

Relevant source projects already connect pangenome openness, pathway composition, geography, and capability dependency. This opportunity tests whether KO innovation adds a new explanatory layer to those analyses.

Work Package

Join KO innovation signals to pangenome openness metrics and pathway ecology outputs. Compare against baseline annotation counts, pathway presence, and species composition. Record which signals are robust and which are artifacts of annotation density.

Decision Use

Successful reuse would promote Functional Innovation KO Atlas and give pangenome topics a stronger functional drill-down. Weak reuse would keep the product as a candidate and narrow its recommended use.