KEScience Tenant and Fitness Evidence

Role In The Observatory

The KEScience fitness data turns gene presence into tested phenotype. It is the key evidence stream for essentiality, metal stress, metabolic dependency, cofitness, and annotation repair.

Agent Use

Use this tenant when a claim depends on whether a gene matters under a condition. Do not substitute annotation for fitness when the Fitness Browser has relevant data.

Caveat

Fitness evidence is condition-specific and organism-specific. Absence of a signal is not proof of absence of function outside the assayed context.