ModelSEED Biochemistry

kbase_msd_biochemistry

Tenant: KBase · Snapshot 2026-04-29T21:35:53.838483+00:00

Primary

Schema status

discovered

Curation status

curated

Source

berdl-spark-connect://metrics.berdl.kbase.us:443

Philosophy

Enable metabolic modeling and pathway analysis. Map genes to reactions, understand metabolic capabilities, and support flux balance analysis.

Data sources: ModelSEED KEGG MetaCyc

Citation & Attribution

Provider: ModelSEED / Henry Lab

Website: https://modelseed.org/

Scale

4
tables

Schema Browser

structure

Column Type Description

Sample Queries

Get reactions

SELECT *
FROM kbase_msd_biochemistry.reaction
LIMIT 20

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Atlas Pages

data tenant

KBase Tenant and Foundational Genome Data

KBase-provided genome, pangenome, phenotype, and ModelSEED resources that form the core comparative-genomics substrate.

data type

Metabolism, Biochemistry, and Pathways

Biochemical reference data and predicted or measured metabolic capabilities that support pathway-level interpretation and community design.

derived product

Functional Innovation KO Atlas

Reusable clade-level functional innovation and acquisition-depth outputs from the ecological agora project.

data collection

Biochemistry

ModelSEED biochemical reactions, compounds, and stoichiometry for metabolic modeling

direction

Fitness-validated community design

Design microbial communities using tolerance, metabolic capability, measured dependency, and risk annotations.

hypothesis

Cross-cohort metabolite ecotypes require batch correction

Absolute-intensity metabolite ecotypes are dominated by cohort batch effects unless corrected before clustering.

hypothesis

Open pangenomes carry broader pathway diversity

Species with more open pangenomes have broader metabolic pathway repertoires after controlling for genome count and taxonomy.

opportunity

CF Formulation Score Reuse Test

Find a first downstream consumer for CF formulation scores by testing whether ranked carbon contexts improve strain or community design decisions.

opportunity

Functional Innovation KO Atlas Reuse Test

Test whether the Functional Innovation KO Atlas helps explain pangenome, pathway, or plant-microbiome signals beyond generic annotation summaries.

opportunity

Plant Microbiome Function Validation

Validate whether plant microbiome functional signals persist across ecotype labels, pangenome context, and environmental metadata.

opportunity

Derived Product Readiness Burn-Down

Review candidate and promoted derived products to close missing consumers, artifacts, caveats, and review routes before they become default inputs.

topic

Host Microbiome Translation

Synthesis of IBD phage targeting, formulation design, metabolomics caveats, patient stratification, and intervention cost accounting.

topic

Plant Microbiome Function and Agriculture

Synthesis of plant-associated microbial function, beneficial/pathogenic duality, compartment structure, PGP markers, and pangenome ecology.

topic

Metabolic Capability, Dependency, and Community Design

Synthesis of GapMind capability, fitness dependency, metabolic models, community ecology, and design-ready derived data.

Atlas Reuse

Start Exploring

Access the full ModelSEED Biochemistry data through BERDL JupyterHub.

Open JupyterHub